{"id":3138,"date":"2023-11-22T06:44:50","date_gmt":"2023-11-22T06:44:50","guid":{"rendered":"http:\/\/drhimanshuyadav.com\/surgery-is-no-longer-supported-for-rectal-cancer\/"},"modified":"2023-11-22T06:44:50","modified_gmt":"2023-11-22T06:44:50","slug":"surgery-is-no-longer-supported-for-rectal-cancer","status":"publish","type":"post","link":"https:\/\/drhimanshuyadav.com\/blog\/surgery-is-no-longer-supported-for-rectal-cancer\/","title":{"rendered":"Surgery is no longer supported for rectal cancer"},"content":{"rendered":"<div id=\"article-content\">\n<h3 class=\"sectionTitle\">    Top line: <\/h3>\n<p>Proctectomy and other surgeries are becoming less popular for the treatment of stages II and III. <a class=\"cl_ref_article_281237\" href=\"https:\/\/emedicine.medscape.com\/article\/281237-overview\" target=\"_blank\" rel=\"noopener\">rectal cancer<\/a> In the US. <\/p>\n<h3 class=\"sectionTitle\">    methodology: <\/h3>\n<ul>\n<li>\n<p>The National Comprehensive Cancer Network recommends observation rather than surgery if a patient with rectal cancer has a complete clinical response to neoadjuvant therapy, but patients and healthcare providers It is unclear how often this organ-sparing approach is chosen.<\/p>\n<\/li>\n<li>\n<p>To find out, researchers looked at 175,545 adults in the National Cancer Database who were treated for rectal adenocarcinoma from 2006 to 2020.<\/p>\n<\/li>\n<li>\n<p>The research team evaluated changes in the proportion of patients who received chemotherapy or radiation therapy without tumor resection, transanal local excision, or rectal resection. <\/p>\n<\/li>\n<li>\n<p>The mean age of patients was 63 years, 39.7% were female, 17.4% had stage 1 disease, 24.7% had stage 2A-C disease, and 32.1% had stage 3A-C tumors. The tumor stage was unknown in more than a quarter of the patients.<\/p>\n<\/li>\n<\/ul>\n<h3 class=\"sectionTitle\">    remove: <\/h3>\n<ul>\n<li>\n<p>The annual absolute rate of organ preservation increased by more than 50% from 18.4% in 2006 to 28.2% in 2020.<\/p>\n<\/li>\n<li>\n<p>Within that period, organ preservation rates increased from 19.5% to 32.5% for patients with stage 2A-C, an increase of approximately 67%. In patients with stage 2A-C, it increased from 16.2% to 29.1%, an increase of approximately 80%.  16.5% to 26.6% (approximately 60% percentage increase) for patients with 3A-C disease and unstaged disease.<\/p>\n<\/li>\n<li>\n<p>However, among patients with stage I rectal cancer, the rate of rectal resection increased by 6.1 percentage points, or approximately 30%, from 20.3% to 26.4%.<\/p>\n<\/li>\n<li>\n<p>Among patients who actually underwent surgery, the proportion with a complete pathologic response to neoadjuvant therapy nearly tripled, increasing from 6.5% to 18.8%.<\/p>\n<\/li>\n<\/ul>\n<h3 class=\"sectionTitle\">    in fact: <\/h3>\n<p>&#8220;This case series demonstrates that rectal cancer is increasingly being managed medically, especially among patients whose treatment has traditionally relied on proctectomy,&#8221; the authors concluded. ing. However, there is a lack of protocols to standardize this approach, so &#8220;establishing quality standards for organ preservation is an urgent task that requires the involvement of all stakeholders, including patients.&#8221;<\/p>\n<h3 class=\"sectionTitle\">    sauce: <\/h3>\n<p>The study, led by Anthony Loria, MD, MSCI, of the University of Rochester, New York, was published online on November 9th. <a href=\"https:\/\/jamanetwork.com\/journals\/jamaoncology\/article-abstract\/2811795\" target=\"_blank\" rel=\"noopener\"> <em>JAMA Oncology.<\/em> <\/a> <\/p>\n<h3 class=\"sectionTitle\">    Limitations: <\/h3>\n<p>The proportion of people who required surgery for recurrence, patient and institutional factors associated with organ preservation, and overall survival outcomes were not addressed.<\/p>\n<h3 class=\"sectionTitle\">    Disclosure: <\/h3>\n<p>No external funding was reported, and the investigators did not report any relevant financial relationships.<\/p>\n<p> <em>M. Alexander Otto is a physician assistant who earned a master&#8217;s degree in medicine and a degree in journalism from Newhouse. He is an award-winning medical journalist who worked for several major news organizations before joining Medscape. Alex is also an MIT Knight Fellow in Science Journalism.  Email: <\/em>  <em>aotto@mdedge.com<\/em>  <\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Top line: Proctectomy and other surgeries are becoming less popular for the treatment of stages II and III. rectal cancer In the US. methodology: The National Comprehensive Cancer Network recommends observation rather than surgery if a patient with rectal cancer has a complete clinical response to neoadjuvant therapy, but patients and healthcare providers It is &#8230; <a title=\"Surgery is no longer supported for rectal cancer\" class=\"read-more\" href=\"https:\/\/drhimanshuyadav.com\/blog\/surgery-is-no-longer-supported-for-rectal-cancer\/\" aria-label=\"Read more about Surgery is no longer supported for rectal cancer\">Read more<\/a><\/p>\n","protected":false},"author":2,"featured_media":3139,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[175],"tags":[3,2110,12,2111,545],"class_list":["post-3138","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-anal-cancer","tag-cancer","tag-longer","tag-rectal","tag-supported","tag-surgery"],"_links":{"self":[{"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/posts\/3138","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/comments?post=3138"}],"version-history":[{"count":0,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/posts\/3138\/revisions"}],"wp:attachment":[{"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/media?parent=3138"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/categories?post=3138"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/tags?post=3138"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}