{"id":3146,"date":"2023-11-24T05:33:58","date_gmt":"2023-11-24T05:33:58","guid":{"rendered":"http:\/\/drhimanshuyadav.com\/investigation-of-the-relationship-and-influencing-factors-among-h-pylori-infection-crp-and-p-s6k1-expression\/"},"modified":"2023-11-24T05:33:58","modified_gmt":"2023-11-24T05:33:58","slug":"investigation-of-the-relationship-and-influencing-factors-among-h-pylori-infection-crp-and-p-s6k1-expression","status":"publish","type":"post","link":"https:\/\/drhimanshuyadav.com\/blog\/investigation-of-the-relationship-and-influencing-factors-among-h-pylori-infection-crp-and-p-s6k1-expression\/","title":{"rendered":"Investigation of the relationship and influencing factors among H. pylori infection, CRP, and p-S6K1 expression"},"content":{"rendered":"<div>\n<p><span style=\"font-weight: 400;\">The following is a summary of &#8220;Analysis of correlation and influencing factors between colon polyps, Helicobacter pylori infection, and p-S6K1 expression&#8221; published in the November 2023 issue. <\/span><i><span style=\"font-weight: 400;\">Infection<\/span><\/i><span style=\"font-weight: 400;\">    Jia et al.<\/span><\/p>\n<hr\/>\n<p><span style=\"font-weight: 400;\">Researchers initiated a retrospective study to analyze the relationship between colorectal polyps (CRP) and Helicobacter pylori (<\/span><i><span style=\"font-weight: 400;\">Helicobacter pylori<\/span><\/i><span style=\"font-weight: 400;\">) infection, and the relationship between CRP and phosphorylated ribosomal protein S6 kinase (p-S6K1) expression to identify potential influencing factors.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">They selected 191 subjects who underwent colonoscopy. Of these, 141 patients were diagnosed with CRP, while the remaining 50 subjects had no significant colorectal abnormalities.  Her 141 CRP patients were classified as follows: <\/span><i><span style=\"font-weight: 400;\">Helicobacter pylori<\/span><\/i><span style=\"font-weight: 400;\">&#8211; with positive group (n = 89) <\/span><i><span style=\"font-weight: 400;\">Helicobacter pylori<\/span><\/i><span style=\"font-weight: 400;\">-Based on negative group (n = 52) <\/span><i><span style=\"font-weight: 400;\">Helicobacter pylori<\/span><\/i><span style=\"font-weight: 400;\">    Test results.  We examined p-S6K1 expression in CRP tissues and analyzed the relationship between expression and clinicopathological characteristics of CRP patients.  Logistic analysis was performed to identify factors influencing the occurrence of CRP.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The results showed that there were significant differences in pathological type, disease location, number and size of polyps between the two. <\/span><i><span style=\"font-weight: 400;\">Helicobacter pylori<\/span><\/i><span style=\"font-weight: 400;\">&#8211; with negative group <\/span><i><span style=\"font-weight: 400;\">Helicobacter pylori<\/span><\/i><span style=\"font-weight: 400;\">-Positive group (<\/span><i><span style=\"font-weight: 400;\">P<\/span><\/i><span style=\"font-weight: 400;\"><0.001, <\/span><i><span style=\"font-weight: 400;\">P<\/span><\/i><span style=\"font-weight: 400;\">=0.037, <\/span><i><span style=\"font-weight: 400;\">P<\/span><\/i><span style=\"font-weight: 400;\">=0.042, and <\/span><i><span style=\"font-weight: 400;\">P<\/span><\/i><span style=\"font-weight: 400;\">=0.039). The percentage of p-S6K1 positive expression in polyp tissues exceeded that in normal and parapolyp tissues (<\/span><i><span style=\"font-weight: 400;\">P<\/span><\/i><span style=\"font-weight: 400;\"><0.001).  The p-S6K1-negative group showed significant differences in the number and pathological type of polyps and the presence or absence of pedicles compared to the p-S6K1-positive group (<\/span><i><span style=\"font-weight: 400;\">P<\/span><\/i><span style=\"font-weight: 400;\">=0.006, <\/span><i><span style=\"font-weight: 400;\">P<\/span><\/i><span style=\"font-weight: 400;\"><0.001, and <\/span><i><span style=\"font-weight: 400;\">P<\/span><\/i><span style=\"font-weight: 400;\">=0.012). BMI was determined by logistic multifactorial analysis. <\/span><i><span style=\"font-weight: 400;\">Helicobacter pylori<\/span><\/i><span style=\"font-weight: 400;\">    Infection, smoking history, ApoB, Lp(a), and p-S6K1 positive expression as risk factors for CRP development (<\/span><i><span style=\"font-weight: 400;\">P<\/span><\/i><span style=\"font-weight: 400;\">=0.025, <\/span><i><span style=\"font-weight: 400;\">P<\/span><\/i><span style=\"font-weight: 400;\">=0.020, <\/span><i><span style=\"font-weight: 400;\">P<\/span><\/i><span style=\"font-weight: 400;\">=0.010, <\/span><i><span style=\"font-weight: 400;\">P<\/span><\/i><span style=\"font-weight: 400;\">=0.005, <\/span><i><span style=\"font-weight: 400;\">P<\/span><\/i><span style=\"font-weight: 400;\">=0.043, and <\/span><i><span style=\"font-weight: 400;\">P<\/span><\/i><span style=\"font-weight: 400;\"><0.001).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">they concluded that <\/span><i><span style=\"font-weight: 400;\">Helicobacter pylori<\/span><\/i><span style=\"font-weight: 400;\">    Infection and p-S6K1 expression are associated with the development of colorectal polyps and require further research on prevention and screening measures.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">sauce: <\/span><a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-023-08791-y\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-023-08791-y<\/span><\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>The following is a summary of &#8220;Analysis of correlation and influencing factors between colon polyps, Helicobacter pylori infection, and p-S6K1 expression&#8221; published in the November 2023 issue. Infection Jia et al. Researchers initiated a retrospective study to analyze the relationship between colorectal polyps (CRP) and Helicobacter pylori (Helicobacter pylori) infection, and the relationship between CRP &#8230; <a title=\"Investigation of the relationship and influencing factors among H. pylori infection, CRP, and p-S6K1 expression\" class=\"read-more\" href=\"https:\/\/drhimanshuyadav.com\/blog\/investigation-of-the-relationship-and-influencing-factors-among-h-pylori-infection-crp-and-p-s6k1-expression\/\" aria-label=\"Read more about Investigation of the relationship and influencing factors among H. pylori infection, CRP, and p-S6K1 expression\">Read more<\/a><\/p>\n","protected":false},"author":2,"featured_media":3147,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[2,737,738,740,741,2115,742,1501],"class_list":["post-3146","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","tag-among","tag-expression","tag-factors","tag-infection","tag-influencing","tag-investigation","tag-ps6k1","tag-relationship"],"_links":{"self":[{"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/posts\/3146","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/comments?post=3146"}],"version-history":[{"count":0,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/posts\/3146\/revisions"}],"wp:attachment":[{"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/media?parent=3146"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/categories?post=3146"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/tags?post=3146"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}