{"id":3313,"date":"2023-12-12T08:41:44","date_gmt":"2023-12-12T08:41:44","guid":{"rendered":"http:\/\/drhimanshuyadav.com\/premature-infants-in-their-first-year-of-life-are-at-increased-risk-of-appendicitis\/"},"modified":"2023-12-12T08:41:44","modified_gmt":"2023-12-12T08:41:44","slug":"premature-infants-in-their-first-year-of-life-are-at-increased-risk-of-appendicitis","status":"publish","type":"post","link":"https:\/\/drhimanshuyadav.com\/blog\/premature-infants-in-their-first-year-of-life-are-at-increased-risk-of-appendicitis\/","title":{"rendered":"Premature infants in their first year of life are at increased risk of appendicitis."},"content":{"rendered":"<div data-component=\"ArticleContent\">\n<div class=\"article__content--header\">\n<div class=\"article__posted-date\">\n<p>    December 6, 2023 <\/p>\n<p>    2 minute read <\/p>\n<\/p><\/div>\n<\/div>\n<div class=\"mobile-trust-box\">\n<div class=\"row\">\n<div class=\"col-12 col-md-6 offset-md-1 offset-xl-0 col-xl-12\">\n<div class=\"d-none\" data-component=\"EmailTopicAlert\" data-module=\"Subspecialty Email Topic Alerts Top\" data-manage-email-link=\"\/footer\/account-information\/my-account\/email-subscriptions-and-alerts#emailAlerts\">\n  <hidden data-setting-item=\"d265901d-6d37-49c7-a8f6-c7bf19a02509\"\/><br \/>\n  <hidden data-crm-source=\"Subspecialty Topic Alert\"\/><\/p>\n<div class=\"email-alert-button d-none\" data-topic-button=\"not-subscribed\">\n<p>&#13;<br \/>\n      <span data-module-track-action=\"Email Alerts TOP_Click_Healio News Article\" data-module-track-label=\"Email Alerts TOP_Healio News Article\">&#13;<br \/>\n        <i class=\"fas fa-plus-circle\"\/>Add topics to email alerts<br \/>\n      <\/span>&#13;\n    <\/p>\n<div class=\"email-alert-inner collapse u1a1387b2a5af4c709a99d791029724af\">\n<div class=\"email-alert-dialogue\">\n<p>Receive an email when a new article is posted <span data-content=\"topic-title\"\/>&#13;\n        <\/p>\n<div class=\"d-none\" data-sign-up-type=\"unknown\">\n<p>          Enter your email address to receive emails when new articles are posted. <span data-content=\"topic-title\"\/>.<\/p><\/div>\n<\/p><\/div>\n<p>      <button type=\"button\" class=\"btn btn-primary\" data-loading-text=\"Loading &lt;i class=\" fa=\"\" fa-spinner=\"\" fa-spin=\"\">&#8221; data-action=&#8221;subscribe&#8221;> Subscribe<br \/>\n      <\/button>\n    <\/div>\n<\/p><\/div>\n<div class=\"d-none\" data-topic-modal=\"failed\">    <strong>Your request could not be processed. Please try again later. If you continue to experience this issue, please contact us at customerservice@slackinc.com.<\/strong>  <\/p>\n<p><button data-dismiss=\"modal\" class=\"btn btn-primary btn-lg btn-block\">Return to Helio<\/button><\/p>\n<\/div>\n<\/div><\/div>\n<\/p><\/div>\n<\/p><\/div>\n<h2>Important points:<\/h2>\n<ul>\n<li>Preterm birth was significantly associated with the onset of appendicitis before the age of 1 year.<\/li>\n<li>Diagnosis requires consideration of history of preterm birth.<\/li>\n<\/ul>\n<p>Preterm infants have an increased risk of developing appendicitis during their first year of life, according to a study published today. <i>Pediatrics<\/i>.<\/p>\n<p>\u201cGiven the low frequency of acute appendicitis in infants and the atypical presentation of acute appendicitis in nonverbal patients, delays in diagnosis and treatment are almost certain.\u201d <b>Yakun<\/b><b>    Dr. Liu,<\/b> and colleagues from the Department of General Surgery, Dongzhou University Children&#8217;s Hospital in Suzhou, Jiangsu Province, China. <\/p>\n<figure class=\"figure article__og-image\">&#13;\n    <picture>&#13;<source srcset=\"https:\/\/www.healio.comhttps:\/\/www.healio.comhttps:\/\/www.healio.com\/~\/media\/slack-news\/neurology\/miscellaneous\/images\/preterm-infant_106379439.webp?w=476\" media=\"(max-width: 768px)\">&#13;<source srcset=\"https:\/\/www.healio.com\/~\/media\/slack-news\/neurology\/miscellaneous\/images\/preterm-infant_106379439.webp?w=800\" media=\"(max-width: 992px)\">&#13;<source srcset=\"https:\/\/www.healio.com\/~\/media\/slack-news\/neurology\/miscellaneous\/images\/preterm-infant_106379439.webp?w=595\" media=\"(max-width: 1200px)\">&#13;<source srcset=\"https:\/\/www.healio.comhttps:\/\/www.healio.comhttps:\/\/www.healio.com\/~\/media\/slack-news\/neurology\/miscellaneous\/images\/preterm-infant_106379439.webp?w=476\" media=\"(min-width: 1200px)\">&#13;<source srcset=\"https:\/\/www.healio.comhttps:\/\/www.healio.comhttps:\/\/www.healio.com\/~\/media\/slack-news\/neurology\/miscellaneous\/images\/preterm-infant_106379439.webp?w=476\">&#13;<br \/>\n&#13;<br \/>\n      <img decoding=\"async\" src=\"https:\/\/www.healio.com\/~\/media\/slack-news\/neurology\/miscellaneous\/images\/preterm-infant_106379439.jpg?w=800\" alt=\"Preterm baby_106379439\" class=\"figure-img img-fluid\" width=\"800\"\/>&#13;<br \/>\n    <\/source><\/source><\/source><\/source><\/source><\/picture>&#13;<figcaption class=\"figure-caption\">According to a study, preterm infants have an increased risk of appendicitis during the first year of life. <i>Pediatrics<\/i>. <i>image<\/i><i>:Adobe stock<\/i>&#13;<br \/>\n    <\/figcaption>&#13;<br \/>\n  <\/figure>\n<p>&#8220;Historically, bacterial invasive infection was thought to be an important factor in the development and progression of appendicitis,&#8221; the researchers continued.  &#8220;It has been hypothesized that preterm infants may be at higher risk for appendicitis due to their immature immune system and increased susceptibility to infections. However, there is a potential link between preterm birth and infant appendicitis. The relationship has not yet been investigated.\u201d<\/p>\n<p>This retrospective, multicenter case-control study included 106 infants diagnosed with appendicitis (median age 2.4 months, 68.9% boys, 34% history of preterm delivery) and 1,060 healthy controls (median age 2.5 months). , investigated this association. month, 54.6% boys, history of preterm birth, 11.6%).  Infants from three children&#8217;s hospitals and tertiary care centers were grouped by age: neonates 0 days to 28 days old and older infants >28 days old but less than 1 year old.<\/p>\n<p>Using univariate analysis, researchers found that preterm birth was significantly associated with the onset of appendicitis before the age of 1 year (OR = 4.23; 95% CI, 2.67-6.7). Other factors associated with increased risk of infantile appendicitis include male gender (OR = 1.91; 95% CI, 1.25-2.94) and weight-for-age. <i>z<\/i> score (OR = 0.72; 95% CI, 0.64-0.81) and fed exclusively with formula (OR = 2.95; 95% CI, 1.77-4.91).<\/p>\n<p>Multivariate analysis still showed a significant association between preterm birth and appendicitis (adjusted OR = 3.32; 95% CI, 1.76-6.24), which was similar in subgroup analyzes for both neonates (aOR = 4.56; 95% CI, 2.14-9.71). and older infants (aOR = 3.63; 95% CI, 1.72-7.65).<\/p>\n<p>The researchers also found that 72.6% of the appendicitis group presented with perforated appendicitis, but a history of preterm birth was not associated with the incidence of perforation (OR = 0.79; 95% CI, 0.32-1.91) .<\/p>\n<p>&#8220;Preterm infants are at increased risk of appendicitis during the first year of life,&#8221; Liu et al. write.  &#8220;Diagnostic algorithms for infantile appendicitis should consider history of preterm birth. Future studies are warranted to expand knowledge about infantile appendicitis and facilitate timely diagnosis.&#8221;<\/p>\n<div class=\"publisher-logo\">\n    <span>Issuer:<\/span><br \/>\n    <img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.healio.com\/~\/media\/h5\/feature\/news\/publogos\/idc.svg?h=28&amp;w=167&amp;la=en&amp;hash=8CC8A6E7BBEA24BE550B22728F1DED49\" class=\"logo-img\" width=\"167\" height=\"28\" alt=\"infectious diseases in children\"\/>\n  <\/div>\n<div class=\"article__content--footer\">\n<div class=\"d-none\" data-component=\"EmailTopicAlert\" data-module=\"Subspecialty Email Topic Alerts Top\" data-manage-email-link=\"\/footer\/account-information\/my-account\/email-subscriptions-and-alerts#emailAlerts\">\n  <hidden data-setting-item=\"d265901d-6d37-49c7-a8f6-c7bf19a02509\"\/><br \/>\n  <hidden data-crm-source=\"Subspecialty Topic Alert\"\/><\/p>\n<div class=\"email-alert-button d-none\" data-topic-button=\"not-subscribed\">\n<p>&#13;<br \/>\n      <span data-module-track-action=\"Email Alerts TOP_Click_Healio News Article\" data-module-track-label=\"Email Alerts TOP_Healio News Article\">&#13;<br \/>\n        <i class=\"fas fa-plus-circle\"\/>Add topics to email alerts<br \/>\n      <\/span>&#13;\n    <\/p>\n<div class=\"email-alert-inner collapse u1a1387b2a5af4c709a99d791029724af\">\n<div class=\"email-alert-dialogue\">\n<p>Receive an email when a new article is posted <span data-content=\"topic-title\"\/>&#13;\n        <\/p>\n<div class=\"d-none\" data-sign-up-type=\"unknown\">\n<p>          Enter your email address to receive emails when new articles are posted. <span data-content=\"topic-title\"\/>.<\/p><\/div>\n<\/p><\/div>\n<p>      <button type=\"button\" class=\"btn btn-primary\" data-loading-text=\"Loading &lt;i class=\" fa=\"\" fa-spinner=\"\" fa-spin=\"\">&#8221; data-action=&#8221;subscribe&#8221;> Subscribe<br \/>\n      <\/button>\n    <\/div>\n<\/p><\/div>\n<div class=\"d-none\" data-topic-modal=\"failed\">    <strong>Your request could not be processed. 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