{"id":3814,"date":"2024-02-09T20:52:01","date_gmt":"2024-02-09T20:52:01","guid":{"rendered":"http:\/\/drhimanshuyadav.com\/study-reveals-differences-in-early-onset-colorectal-cancer\/"},"modified":"2024-02-09T20:52:01","modified_gmt":"2024-02-09T20:52:01","slug":"study-reveals-differences-in-early-onset-colorectal-cancer","status":"publish","type":"post","link":"https:\/\/drhimanshuyadav.com\/blog\/study-reveals-differences-in-early-onset-colorectal-cancer\/","title":{"rendered":"Study reveals differences in early-onset colorectal cancer"},"content":{"rendered":"<div>\n<p>CLEVELAND \u2014 RECENT <a href=\"https:\/\/newsroom.clevelandclinic.org\/2024\/02\/05\/cleveland-clinic-research-reveals-unique-tumor-related-bacteria-tied-to-young-onset-colorectal-cancer\/\" target=\"_blank\" rel=\"noopener\">Research by Cleveland Clinic<\/a> Differences have been shown in the tumor-associated bacteria associated with early-onset colorectal cancer, a finding that could lead to new screenings and treatments. <\/p>\n<div class=\"embedcode\">\n<hr style=\"height: 2px; border-width: 0; background-color: #042d4d;\"\/>\n<h4 style=\"text-indent: 10px;\"><b>What you need to know<\/b><\/h4>\n<h5>\n<ul>\n<li>This study <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S235239642400015X\" target=\"_blank\" rel=\"noopener\">e-biomedicine<\/a>used gene sequencing technology to compare tissue samples from 136 young-onset colorectal cancer patients with tissue samples from 140 patients with the same disease and average age.<\/li>\n<p><\/p>\n<li>Researchers identified unique tumor-associated bacteria in the younger group and also found that they were more likely to have left-sided, rectal, and advanced-stage tumors, the Cleveland Clinic said.<\/li>\n<p><\/p>\n<li>of <a href=\"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/epdf\/10.3322\/caac.21708?src=getftr\" target=\"_blank\" rel=\"noopener\">American Cancer Society<\/a> In the state, the incidence of young-onset colorectal cancer is increasing by 1.5% each year, and the mortality rate is also increasing by 1.2% annually.<\/li>\n<\/ul>\n<\/h5>\n<hr style=\"height: 2px; border-width: 0; background-color: #042d4d;\"\/>\n<\/div>\n<p>This study <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S235239642400015X\" target=\"_blank\" rel=\"noopener\">e-biomedicine<\/a>used gene sequencing technology to compare tissue samples from 136 young-onset colorectal cancer patients with tissue samples from 140 patients with the same disease of average age. Researchers identified unique tumor-associated bacteria in the younger group and also found that they were more likely to have left-sided, rectal, and advanced-stage tumors, the Cleveland Clinic said. <\/p>\n<p>&#8220;The unexplained increase in young-onset colorectal cancer is very concerning,&#8221; said Dr. Alok Khorana, a Cleveland Clinic oncologist and principal investigator of the study.  &#8220;Our team found that bacteria are more abundant and compositionally distinct in tumors from younger-onset patients. These insights may lead to a better understanding of disease causes, new preventive approaches, diagnostic markers, and It helps us understand therapeutic targets.\u201d <\/p>\n<p>of <a href=\"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/epdf\/10.3322\/caac.21708?src=getftr\" target=\"_blank\" rel=\"noopener\">American Cancer Society<\/a> In the state, the incidence of young-onset colorectal cancer is increasing by 1.5% annually, and the mortality rate is also increasing by 1.2% annually. <a href=\"https:\/\/watermark.silverchair.com\/djw322.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAA1MwggNPBgkqhkiG9w0BBwagggNAMIIDPAIBADCCAzUGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMRO9XAvlrfmXW22WcAgEQgIIDBlMfQYrgV7Q4G5GqMGOcVnobxPiQSZiCQ2UDz565qJmD9uADbejnVh6U4L7dlibrPgZfFcs3_KvH7DO6QVc_2kPLMcZY2kwVPX1X4d9iOg4-bb0Xv0NrXjUUucicK046_h5mWueuU9iaxT2hL353PNHUZopuK3O5jdI0nAQdbeMU9K8y1Kk1mcPBbHcl1qBH6QWxSyzaNrYSGXBY_V4mUaSD4PLtfTCwFXBk-biQiiucf-GMPO2Fw97qC48geBoY45ISK2P0iFQF3EdO3rYy6Y3N5qmGvVNLLzH2fgf0Hb66LfZhFOgV02uQLGUP4XNGEtNQAbQ73hhGRIepBZuEfcx8IQuAHugQDu99P9DvCTIzlLzxpHyXhMEKtud6PI9ytf6pYaqSV2kovRd5i8Uyr3IkTuaxbKKtxiy7draUXeUgwhB-9ThrK2e3NH6LvHvkWd9HyQ3r50c2WKuWofNb_x7M6Deuv2dX94UCHm40al6XX18GzF9KOxtsVOT44finAtF4nQ8Nl5rkEVt7TpVBL9wwJ_z_uGFGJyi3Ll4OhGhuJh-myiWnRbaupLvXwIg0wbKH2EszH0-97gJTESrd335EiyBc97LRYCCGfHysBMSfQGFL9TP7kejt2lRO4kZroBqzglJi2Mcm1p2DrUJfcv-vX_YH4H-JaKAlqaXMxoFtHSymOK00-KGngAkuGRJyOVTG0B-zdDlrQeKyqUW7mbL3Mr1Z4fTA6sANzjiyNgnHyInKnH8ZjK0GVXeTPR0TplVYvgLEPqFmi6e4t5GPkQPDrWJanSpFDrn9nEOhuqBCyWkjSkrnj_jt86FsUk4ohDiu_uiWgddddkU7Q_5EaO_9hNGZfGvmgsSQhc59yYElMDzYi9uORIe9eltD7Fa-0Qp8GwA8B4oSTPpmPKWI1Xce38dVsjS_rbMxSZKLVkM1L_uDnafphSfPCJkmyLLsq61lAw4cqoHn21p_kMlIWKPfhsOvl7chGpMJX8g2bUuwprjLT96x21AmO2rxNzPmDgRqcvBJUQ\" target=\"_blank\" rel=\"noopener\">National Cancer Institute Journal Report<\/a> If this trend continues, it is estimated that by 2030, the incidence of rectal cancer will quadruple and the incidence of colon cancer will double in this age group.<\/p>\n<p>&#8220;Detailed characterization of this microbial signature of juvenile disease can open our eyes to new screening biomarkers and drugs that target the bacteria involved,&#8221; said the study&#8217;s authors, Cleveland Clinic Research Institute. said Dr. Simoli Barot. <\/p>\n<p>Dr Nasir Sangwan, another author of the study, said further research was needed, including into lifestyle factors and how they contribute to disease and influence gut bacteria.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>CLEVELAND \u2014 RECENT Research by Cleveland Clinic Differences have been shown in the tumor-associated bacteria associated with early-onset colorectal cancer, a finding that could lead to new screenings and treatments. What you need to know This study e-biomedicineused gene sequencing technology to compare tissue samples from 136 young-onset colorectal cancer patients with tissue samples from &#8230; <a title=\"Study reveals differences in early-onset colorectal cancer\" class=\"read-more\" href=\"https:\/\/drhimanshuyadav.com\/blog\/study-reveals-differences-in-early-onset-colorectal-cancer\/\" aria-label=\"Read more about Study reveals differences in early-onset colorectal cancer\">Read more<\/a><\/p>\n","protected":false},"author":2,"featured_media":3815,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[3,24,1064,2562,392,342],"class_list":["post-3814","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-colorectal-cancer","tag-cancer","tag-colorectal","tag-differences","tag-earlyonset","tag-reveals","tag-study"],"_links":{"self":[{"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/posts\/3814","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/comments?post=3814"}],"version-history":[{"count":0,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/posts\/3814\/revisions"}],"wp:attachment":[{"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/media?parent=3814"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/categories?post=3814"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/tags?post=3814"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}