{"id":3896,"date":"2024-02-18T19:33:50","date_gmt":"2024-02-18T19:33:50","guid":{"rendered":"http:\/\/drhimanshuyadav.com\/do-multivitamin-supplements-lower-the-risk-of-dying-from-colorectal-cancer\/"},"modified":"2024-02-18T19:33:50","modified_gmt":"2024-02-18T19:33:50","slug":"do-multivitamin-supplements-lower-the-risk-of-dying-from-colorectal-cancer","status":"publish","type":"post","link":"https:\/\/drhimanshuyadav.com\/blog\/do-multivitamin-supplements-lower-the-risk-of-dying-from-colorectal-cancer\/","title":{"rendered":"Do multivitamin supplements lower the risk of dying from colorectal cancer?"},"content":{"rendered":"<div>\n<h3><strong>Top line:<\/strong><\/h3>\n<p>Moderate doses of multivitamin supplements appear to reduce the risk of both all-cause and cancer-related death in patients with the following diseases: <a href=\"https:\/\/emedicine.medscape.com\/article\/2500006-overview\" class=\"cl_ref_article\" target=\"_blank\" rel=\"noopener\">colorectal cancer<\/a> (CRC); However, high-dose multivitamin supplements may increase the risk of colorectal cancer-specific death.<\/p>\n<h3><strong>methodology:<\/strong><\/h3>\n<ul>\n<li>Some studies suggest that multivitamin supplements may increase the risk of colon cancer, and other studies suggest that certain components of vitamin C may <a href=\"https:\/\/reference.medscape.com\/drug\/folgard-natalins-rx-multivitamins-344421\" class=\"cl_ref_drugs\" target=\"_blank\" rel=\"noopener\">multivitamin<\/a>vitamins C and D, which may have anti-colon cancer effects.<\/li>\n<li>Because as many as half of CRC survivors take multivitamins, researchers wanted to assess whether multivitamin use affects overall survival in CRC patients.<\/li>\n<li>In the current prospective cohort study, researchers used detailed information obtained from patients in the Nurses&#8217; Health Study and Health Professionals Follow-up Study to study 2,424 patients with stage I-III colorectal cancer. The use and dosage of multivitamin supplements was evaluated.<\/li>\n<li>Participants completed mailed surveys every two years. The survey included questions regarding current use of multivitamin supplements and weekly dosage (0, 1-2, 3-5, 6-9, and >10 tablets).<\/li>\n<li>Researchers evaluated the potential association between multivitamin use and colorectal cancer-related and all-cause mortality.<\/li>\n<\/ul>\n<h3><strong>remove:<\/strong><\/h3>\n<ul>\n<li>During a median follow-up of 11 years, there were 1,512 deaths and 343 cancer deaths.<\/li>\n<li>For patients diagnosed with CRC, taking moderate doses of multivitamins (3 to 5 tablets per week) was associated with a lower risk of cancer-related mortality compared with no multivitamin use. decreased by 45% (adjusted hazard ratio). [aHR],0.55; <em>P<\/em> = .005).<\/li>\n<li>Moderate multivitamin use was also associated with a lower risk of all-cause mortality (aHR, 0.81; <em>P<\/em> = .04) as well as a high dose of 6 to 9 tablets per week (aHR, 0.79; <em>P<\/em> < .001).<\/li>\n<li>However, higher doses of 10 or more tablets per week were associated with a 60% increased risk of cancer-related death (aHR, 1.60; aHR, 1.60). <em>P<\/em> = .02).<\/li>\n<\/ul>\n<h3><strong>in fact:<\/strong><\/h3>\n<p>The results of this study suggest that moderate use of multivitamin supplements may have a survival benefit in patients with colorectal cancer, but higher doses do not. &#8220;Further research is needed before making clinical recommendations for the use of multivitamin supplements,&#8221; the authors said.<\/p>\n<h3><strong>sauce:<\/strong><\/h3>\n<p>The study was led by Ming-ming He of the Sun Yat-sen University Cancer Center in Guangzhou, China. <a href=\"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/full\/10.1002\/cncr.35234\" target=\"_blank\" rel=\"noopener\"><em>cancer<\/em><\/a>.<\/p>\n<h3><strong>Limitations:<\/strong><\/h3>\n<p>Given the observational design of the study, there is potential for residual confounding. Reverse causation and recall bias may also be limitations.<\/p>\n<h3><strong>Disclosure:<\/strong><\/h3>\n<p>This research was funded by the National Institutes of Health, the American Cancer Institute, Wellesley College, Dana-Farber Cancer Institute, and the Entertainment Industry Foundation.  Three study authors reported financial relationships outside of this study.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Top line: Moderate doses of multivitamin supplements appear to reduce the risk of both all-cause and cancer-related death in patients with the following diseases: colorectal cancer (CRC); However, high-dose multivitamin supplements may increase the risk of colorectal cancer-specific death. methodology: Some studies suggest that multivitamin supplements may increase the risk of colon cancer, and other &#8230; <a title=\"Do multivitamin supplements lower the risk of dying from colorectal cancer?\" class=\"read-more\" href=\"https:\/\/drhimanshuyadav.com\/blog\/do-multivitamin-supplements-lower-the-risk-of-dying-from-colorectal-cancer\/\" aria-label=\"Read more about Do multivitamin supplements lower the risk of dying from colorectal cancer?\">Read more<\/a><\/p>\n","protected":false},"author":2,"featured_media":3897,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[175],"tags":[3,24,2622,2623,36,2624],"class_list":["post-3896","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-anal-cancer","tag-cancer","tag-colorectal","tag-dying","tag-multivitamin","tag-risk","tag-supplements"],"_links":{"self":[{"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/posts\/3896","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/comments?post=3896"}],"version-history":[{"count":0,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/posts\/3896\/revisions"}],"wp:attachment":[{"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/media?parent=3896"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/categories?post=3896"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drhimanshuyadav.com\/blog\/wp-json\/wp\/v2\/tags?post=3896"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}