Stage IV colorectal cancer survivor: ‘MD Anderson gave me a second chance’

Jeff Williams has been an FBI agent for 22 years and was in good health when he underwent his first colonoscopy at age 50. At the time, this was the recommended age to begin regular colorectal cancer screening tests. Guidelines later lowered his age to 45. He wasn’t worried, but changed his mind when he […]

New mom’s ‘severe hemorrhoids’ were a symptom of stage 3 colorectal cancer

Christina Kelly was pregnant with her second daughter in 2022 when she developed “severe symptoms.” hemorrhoids” I wasn’t too worried at first because I knew it was a common occurrence during pregnancy. When her symptoms did not subside several months after giving birth, she visited her doctor and ordered a colonoscopy. Kelly was stunned by […]

Some patients with rectal cancer can safely forego neoadjuvant radiation therapy

Preoperative radiation therapy can be safely omitted for many patients with non-locally advanced rectal cancer, according to a study published today. JAMA Oncology. Researchers found that a 50% absolute reduction in the use of radiation therapy at the national level did not worsen outcomes for patients with locally advanced rectal cancer. To examine the impact […]

Next-generation sequencing identifies thousands of cancer patients who cannot receive immunotherapy

Brigham researchers’ next-generation sequencing findings suggest that updating current cancer treatment guidelines could allow approximately 6,000 more patients in the United States to benefit from immunotherapy treatment each year. suggests Immunotherapy is a highly effective treatment for patients whose cancer has mismatch repair defects, and new research identifies more cancer patients who could benefit from […]

BMS completes Phase 3 trial of nivolumab and leratorimab for colorectal cancer

Colorectal cancer: © Peterschreiber.media – Stock.adobe.com Bristol-Myers Squibb is conducting a Phase 3 RELATIVITY study investigating nivolumab (Opdivo) and relatlimab (Opdualag) in patients with previously treated metastatic microsatellite stable (MSS) colorectal cancer (CRC). -123 study (NCT05328908) has been completed and will not progress beyond 1. It is more effective than 4-line treatment because it is […]

Patients with metastatic colorectal cancer may continue to benefit from immunotherapy even after treatment is discontinued

Credit: Pixabay/CC0 Public Domain The majority of patients with metastatic colorectal cancer whose cancer did not progress during initial treatment with immune checkpoint inhibitors (ICIs) had no disease progression for two years after stopping treatment, a new study reports. There is. Research is published in a diary cancer research communication. ICIs have proven effective against […]

Patients with metastatic colorectal cancer may continue to benefit from immunotherapy even after treatment is discontinued

Credit: Pixabay/CC0 Public Domain The majority of patients with metastatic colorectal cancer whose cancer did not progress during initial treatment with immune checkpoint inhibitors (ICIs) had no disease progression for two years after stopping treatment, a new study reports. There is. Research is published in a diary cancer research communication. ICIs have proven effective against […]

Bristol-Myers (BMY) discontinues late-stage colorectal cancer study

bristol myers squib BMY experienced a setback when it decided to cancel the late-stage trial RELATIVITY-123. In this Phase III, randomized, open-label, multicenter study, approximately 700 adult patients with stable microsatellites received a fixed-dose combination of Opdivo (nivolumab) and leratorimab, combined with Stivarga (regorafenib) or It was evaluated in comparison with trifluridine + tipiracil (TAS-102). […]

Bristol-Myers Squibb launches Kibosh into clinical trials for colorectal cancer candidate

Photo: Bristol-Myers Squibb Building in Munich / iStock Tati Campero Bristol-Myers Squibb is discontinuing a clinical trial studying a combination of Opdivo (nivolumab) and leratorimab, called Opdurag, in patients with stable microsatellite metastatic colorectal cancer. Data from a Phase III trial of the combination, known as Relativity-123, was reviewed by an independent data monitoring board […]