RELATIVITY-123 MSS CRC unlikely to reach primary endpoint and will be discontinued

Other trials evaluating fixed-dose combinations of nivolumab and leratorimab as treatments for other tumor types will continue. The phase 3 RELATIVITY-123 trial (NCT05328908) tested nivolumab (Opdivo) and relatlimab (Opdurag) in patients with microsatellite stable (MSS) metastatic colorectal cancer (mCRC) who had disease progression after 1 to 4 days. ) is evaluating the effectiveness of combination […]

FDA approves bevacizumab biosimilar ‘bevacizumab-tnjn’ for lung and colorectal cancer

Credit: U.S. Food and Drug Administration The U.S. Food and Drug Administration (FDA) has approved Bio-Thera Solutions’ bevacizumab (Avastin) biosimilar, bevacizumab-tnjn (Avzivi), for the treatment of lung and colorectal cancer.1 The decision marks Bio-Thera Solutions’ second FDA-approved product in the United States. The decision, announced on December 7, 2023, was based on both clinical and […]

Nivolumab and ipilimumab improve PFS in newly diagnosed metastatic colorectal cancer

The combination of nivolumab (Opdivo) and ipilimumab (Yervoy) improved progression-free survival (PFS) by blinded independent central review (BICR) compared to the chemotherapy chosen by investigators as front-line treatment for microsatellite patients. resulted in statistically significant and clinically meaningful improvements in Meets one of the two primary endpoints of the Phase 3 CheckMate-8HW study in unstable-high […]

Ozempic, Wegovy and other GLP-1 drugs may help prevent colorectal cancer

GLP-1, a type of diabetes and weight loss drug such as Ozempic and Mounjaro, may be associated with a lower risk of colorectal cancer, but more research is needed. Researchers looked at the records of more than 1.2 million diabetic patients and compared GLP-1 to other common anti-diabetic drugs such as metformin and insulin. In […]

Weight loss drugs may help reduce risk

Share on PinterestResearchers are studying the possibility that weight loss drugs can reduce the risk of colorectal cancer.Victor Torres/Stoshi Researchers report that certain type 2 diabetes drugs, which are also used for weight loss, may reduce the risk of colorectal cancer. Obesity and diabetes are both risk factors for colorectal cancer. Maintaining a healthy weight, […]

Promising results from new colorectal cancer treatment

Credit: Peter McCallum Cancer Center A new pill treatment called Divarasib has been shown to be highly effective in treating a difficult type of intestinal (colorectal) cancer associated with the KRAS G12C mutation. research result, natural medicine Today (December 5), researchers showed remarkable results that when divarasib was given in combination with another cancer drug […]

Types of diabetes drugs that may prevent the development of colorectal cancer

Credit: Dr_Microbe/Getty Images Researchers at Case Western Reserve University say certain diabetes drugs used to treat type 2 diabetes may reduce the risk of developing colorectal cancer (CRC). These drugs, called glucagon-like peptide-1 receptor agonists, or GLP-1 RAs, are drugs given by injection that lower blood sugar levels, improve insulin sensitivity, and help with weight […]

BMS Demonstrates Rationale for Opdivo and Yervoy Combination Therapy in First-Line Colorectal Cancer

Photo: California BMS Building Exterior/iStock, hapa bapa Bristol-Myers Squibb on Thursday announced data from the Phase 3 CheckMate-8HW study demonstrating first-line potential for Opdivo (nivolumab) and Yervoy (ipilimumab) combination therapy in metastatic colorectal cancer. . BMS did not provide specific data in Thursday’s announcement, but the company said the combination therapy showed “statistically significant results” […]

Young mother perseveres despite being diagnosed with ‘terminal’ colorectal cancer

Sara Alvarenga is proud of her “very calm” personality. “That’s how I do it,” she says. “Even in traumatic situations, I am very cool, calm and collected.” At 38 years old, she has endured far more traumatic situations than herself. Five years ago, Alvarenga was diagnosed with stage 4 colorectal cancer. Local doctors labeled her […]

Eating more navy beans may help prevent colorectal cancer

Share on PinterestResearch shows that eating more white beans and kidney beans may help colorectal cancer survivors.Daniel Zapata/Getty Images Colorectal cancer is highly treatable in its early stages, but most cases are discovered at an advanced stage. Between 7% and 29% of people treated for colorectal cancer experience recurrence within 5 years. Certain lifestyle changes, […]