First-in-class targeted therapy has potential for colon cancer

Germany’s Merck KGaA (MRK:DE) announced a licensing agreement with New York-based small molecule developer Inspirna.

The agreement is for ompenacrid, a first-in-class SLC6A8 blocker, and will also include other similar follow-on compounds.

Omphenacrid is currently being evaluated in a Phase II trial for second-line treatment of certain people with advanced or metastatic colorectal cancer (mCRC).

Significant improvements have been made…

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