- Each year, nearly 2 million people are diagnosed with colorectal cancer and approximately 935,000 people die from colorectal cancer worldwide.
- Scientists have announced that they have developed a new stool test that is more effective at detecting colorectal cancer than similar tests currently on the market.
- A new stool test could help people be diagnosed earlier.
Scientists have developed a new test that may help detect signs of colorectal cancer earlier and more effectively than current tests, a study led by the Netherlands Cancer Institute suggests. There is.
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Colon cancer is curable if detected early. However, many people are not diagnosed until they are terminally ill.
Every year it’s close to that
Although current stool tests used to detect colorectal cancer have significantly reduced mortality rates from colorectal cancer, they are not perfect and in some cases
“There are new stool tests that are better than current stool tests at detecting pre-cancerous conditions, which means more people with polyps will have colonoscopies and polyps will be removed before they become cancerous. “You will be able to do it,” the doctor said. Cindy Kina colorectal surgeon at Stanford Medicine.
Kim was not involved in the research.
A stool test is not a substitute for a colonoscopy.by
Most colorectal cancer screening tests used around the world are fecal immunochemical tests (FIT), which measure the level of the blood protein hemoglobin in a stool sample.
low level
The new test is Multi-target FIT test (mtFIT) assesses hemoglobin levels along with two other proteins (calprotectin and serpin family F member 2) that are biomarkers for colon cancer.
In the new study, researchers investigated the effectiveness of the mtFIT test compared to the FIT test in 13,187 people aged 55 to 75 in the Netherlands.
They found that the mtFIT test was more effective at detecting signs of colorectal cancer.
The mtFIT test identified 299 people with abnormal protein levels, while the current FIT test identified 159 people with abnormal results.
The new test was better at detecting polyps and growths that required follow-up colonoscopies.
Researchers believe this new test will help doctors identify cases of colorectal cancer earlier, reducing the risk of death from colorectal cancer.
They estimated that the new mtFIT test could reduce colorectal cancer cases by 21% and deaths by 18%.
He said currently available stool tests cannot detect 100% of cancers and high-risk polyps. Anton BilchikMD, PhD, is a surgical oncologist and medical director and director of the gastrointestinal-hepatobiliary program at Providence St. John’s Cancer Institute in Santa Monica, California.
They’re also not as sensitive as colonoscopies, so these stool tests should be done annually to increase the chances of detecting high-risk polyps and cancers, Kin says.
A new, more sensitive stool test could help doctors identify more polyps that have the potential to become cancerous.
“Removing these polyps with a colonoscopy significantly reduces the risk of developing colon cancer,” says Bilchik.
Early detection and treatment will also increase chances of survival, he added.
This test has only been evaluated in the Netherlands, and future studies comparing it with commercially available FIT tests are needed before using the mtFIT test.
A new colorectal screening test may detect more cancers and high-risk polyps than currently available tests, a new study finds. Current stool tests cannot detect all polyps and cancers, and more sensitive tests could prevent many cases of colon cancer and reduce mortality.