Machine learning reveals genetic biomarkers to predict perforated appendicitis in children

Announcement of genetic biomarker for pediatric appendicitis A recent groundbreaking study utilized machine learning to identify genetic biomarkers that can predict perforated appendicitis (PA) in children. Appendicitis is a common pediatric disease that requires urgent surgical intervention, and timely and accurate diagnosis has always been a challenge, especially in the case of perforation. PA has […]

Identification of genetic biomarkers to predict perforated appendicitis in children

A groundbreaking study uses machine learning to identify genetic biomarkers to predict perforated appendicitis in children. This development has the potential to significantly improve patient management decision-making and contribute to evidence-based strategies for antibiotic stewardship. However, due to the low specificity of the biomarker, further studies are required to validate its accuracy, sensitivity, and specificity. […]

To investigate interobserver agreement among endoscopists to grade the morphology and predict histopathology of colorectal lesions in patients with inflammatory bowel disease.

August 19, 2023 Patients diagnosed with inflammatory bowel disease (IBD) are at increased risk of colorectal cancer. To detect precancerous or cancerous polyps early in these patients, current guidelines recommend starting surveillance colonoscopy after 8 to 10 years. IBD Every 1-2 years after diagnosis. Background mucosal inflammation in patients IBD Colorectal lesions can be difficult […]

Predict rectal cancer recurrence

Top line: Immunoscore biopsy quantifies immune cell tumor infiltration in tumor biopsies at baseline; rectal cancer For both local regrowth and distant metastases, careful follow-up is required to prevent recurrence. methodology: Currently, oncologists do not have biomarkers to help select rectal cancer patients for watchful waiting after neoadjuvant chemoradiotherapy or to monitor patients long-term. And […]